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- The design and analysis of sequential clinical trials (1983)

- The design and analysis of sequential clinical trials (Second edition) (1992)

- The design and analysis of sequential clinical trials (1997)

- Bayesian methods for setting sample sizes and choosing allocation ratios in phase II clinical trials with time-to-event endpoints. Statistics in Medicine 2015. 34:1889-1903 .
- Bayesian adaptive dose-escalation procedures for binary and continuous responses utilizing a gain function. Pharmaceutical Statistics 2015. 14:479-487 .
- Bayesian sample sizes for exploratory clinical trials comparing multiple experimental treatments with a control. Statistics in Medicine 2015. 34:2048-2061 .
- Bayesian methods for the design and interpretation of clinical trials in very rare diseases. Statistics in Medicine 2014. 33:4186-4201 .
- One-stage and two-stage designs for phase II clinical trials with survival endpoints. Statistics in Medicine 2014. 33:3830-3843 .
- Designing exploratory cancer trials using change in tumour size as primary endpoint. Statistics in Medicine 2013. 32:2544-2554 .
- A novel Phase I/IIa design for early phase oncology studies and its application in the evaluation of MK-0752 in pancreatic cancer. Statistics in Medicine 2012. 31:1931-1943 .
- A bivariate Bayesian dose-finding procedure applied to a seamless phase I/II trial in rheumatoid arthritis. Pharmaceutical Statistics 2012. 11:476-484 .
- An evaluation of methods for testing hypotheses relating to two endpoints in a single clinical trial. Pharmaceutical Statistics 2012. 11:107-117 .
- Group sequential trials revisited: Simple implementation using SAS. Statistical Methods in Medical Research 2011. 20:635-656 .
- Bayesian procedures for phase I/II clinical trials investigating the safety and efficacy of drug combinations. Statistics in Medicine 2011. 30:1952-1970 .
- An exact method for analysis following a two-stage phase II cancer clinical trial. Statistics in Medicine 2010. 29:- .
- A combined score test for binary and ordinal endpoints from clinical trials. Statistics in Medicine 2010. 29:521-532 .
- A Bayesian dose-finding procedure for phase I clinical trials based only on the assumption of monotonicity. Statistics in Medicine 2010. 29:1808-1824 .
- A simple two-stage design for quantitative responses with application to a study in diabetic neuropathic pain. Pharmaceutical Statistics 2009. 8:125-135 .
- One- and two-stage design proposals for a phase II trial comparing three active treatments with control using an ordered categorical endpoint. Statistics in Medicine 2009. 28:828-847 .
- Updating our aims and scope for the future. Statistics in Medicine 2009. 28:1-2 .
- Evaluation of a sequential global test of improved recovery following stroke as applied to the ICTUS trial of citicoline. Pharmaceutical Statistics 2009. 8:136-149 .
- Action following the discovery of a global association between the whole genome and adverse event risk in a clinical drug-development programme. Pharmaceutical Statistics 2009. 8:287-300 .
- Implementation of a Bayesian Design in a Dose-Escalation Study of an Experimental Agent in Healthy Volunteers. Biometrics 2008. 64:299-308 .
- Fitting models for the joint action of two drugs using $SAS^{(R)}. Pharmaceutical Statistics 2008. 7:272-284 .
- Bayesian sample size for exploratory clinical trials incorporating historical data. Statistics in Medicine 2008. 27:2307-2327 .
- Fitting models for the joint action of two drugs using SAS(R). Pharmaceutical Statistics 2008. 7:272-284 .
- Sequentially testing for a gene-drug interaction in a genomewide analysis. Statistics in Medicine 2008. 27:2022-2034 .
- Estimation following selection of the largest of two normal means. Journal of Statistical Planning and Inference 2008. 138:1629-1638 .
- Incorporating intermediate binary responses into interim analyses of clinical trials: A comparison of four methods. Statistics in Medicine 2008. 27:1646-1666 .
- Sequentially testing for a gene–drug interaction in a genomewide analysis. Statistics in Medicine 2008. 27:2022-2034 .
- Sequential genome-wide association studies for monitoring adverse events in the clinical evaluation of new drugs. Statistics in Medicine 2006. 25:3081-3092 .
- Bayesian decision procedures for binary and continuous bivariate dose-escalation studies. Pharmaceutical Statistics 2006. 5:125-133 .
- The sequential analysis of repeated binary responses: A score test for the case of three time points. Statistics in Medicine 2006. 25:2196-2214 .
- An evaluation of Bayesian designs for dose-escalation studies in healthy volunteers. Statistics in Medicine 2006. 25:433-445 .
- Bayesian decision procedures for dose-escalation based on evidence of undesirable events and therapeutic benefit. Statistics in Medicine 2006. 25:37-53 .
- Design considerations in the sequential analysis of matched case–control data. Statistics in Medicine 2005. 24:853-867 .
- Decision-making in a phase II clinical trial: A new approach combining Bayesian and frequentist concepts. Pharmaceutical Statistics 2005. 4:119-128 .
- The double triangular test in practice. Pharmaceutical Statistics 2004. 3:39-49 .
- An evaluation of a Bayesian method of dose escalation based on bivariate binary responses. Journal of Biopharmaceutical Statistics 2004. 14:969-983 .
- Bayesian ADEPT Developers' Response. Pharmaceutical Statistics 2003. 2:- .
- Incorporating data received after a sequential trial has stopped into the final analysis: Implementation and comparison of methods. Biometrics 2003. 59:701-709 .
- Statistical methods for ordered categorical data based on a constrained odds model. Biometrical Journal 2003. 45:453-470 .
- A score test for binary data with patient non-compliance. Statistics in Medicine 2003. 22:3115-3132 .
- Stopping clinical trials because of treatment ineffectiveness: A comparison of a. Statistics in Medicine 2003. 22:677-687 .
- Software review: Bayesian ADEPT developers' response. Pharmaceutical Statistics 2003. 2:221-221 .
- Stopping clinical trials because of treatment ineffectiveness: a comparison of a futility design with a method of stochastic curtailment. Statistics in Medicine 2003. 22:677-687 .
- A sequential procedure for comparing two experimental treatments with a control. Journal of Biopharmaceutical Statistics 2002. 12:249-265 .
- Comment on ``Heterogeneity in phase I clinical trials: prior elicitation and computation using the continual reassessment method'' (2001V20 p867-882). Statistics in Medicine 2002. 21:1172-1172 .
- Sequential methods in clinical trials∗. Sequential Analysis 2002. 21:285-308 .
- Estimating a treatment effect in survival studies in which patients switch treatment. Statistics in Medicine 2002. 21:2449-2463 .
- Sequential methods in clinical trials1*. Sequential Analysis 2002. 21:285-308 .
- Heterogeneity in phase I clinical trials: prior elicitation and computation using the continual reassessment method by A. Legedza and J. G. Ibrahim, Statistics in Medicine 2001; 20: 867–882. Statistics in Medicine 2002. 21:- .
- Discussion. Environmental and Ecological Statistics 2001. 8:135-136 .
- Easy-to-implement Bayesian methods for dose-escalation studies in healthy volunteers. Biostatistics (Oxford) 2001. 2:47-61 .
- Mid-trial design reviews for sequential clinical trials. Statistics in Medicine 2001. 20:165-176 .
- Confidence intervals for secondary parameters following a sequential test. Journal of the Royal Statistical Society: Series B (Statistical Methodology) 2000. 62:731-745 .
- Formal approaches to safety monitoring of clinical trials in life-threatening conditions. Statistics in Medicine 2000. 19:2899-2917 .
- Decision theoretic designs for phase II clinical trials with multiple outcomes. Biometrics 1999. 55:971-977 .
- A novel Bayesian decision procedure for early-phase dose-finding studies. Journal of Biopharmaceutical Statistics 1999. 9:583-597 .
- A unified theory for sequential clinical trials. Statistics in Medicine 1999. 18:2271-2286 .
- On being the statistician on a Data and Safety Monitoring Board†. Statistics in Medicine 1999. 18:- .
- On being the statistician on a data and safety monitoring board. Statistics in Medicine 1999. 18:3425-3434 .
- Decision theoretic designs for phase II clinical trials with multiple outcomes. Biometrics 1999. 55:971-977 .
- A novel Bayesian decision procedure for early-phase dose-finding studies. Journal of Biopharmaceutical Statistics 1999. 9:583-597 .
- Bayesian decision procedures based on logistic regression models for dose-finding studies. Journal of Biopharmaceutical Statistics 1998. 8:445-467 .
- A method for sequential analysis of survival data with nonproportional hazards. Biometrics 1998. 54:1072-1084 .
- Comment on ``The management of interim analyses in drug development''. Statistics in Medicine 1998. 17:1811-1812 .
- The interpretation of clinical trials of immediate versus delayed therapy. Lifetime Data Analysis 1998. 4:253-263 .
- Confidence interval calculation for a sequential clinical trial of binary responses. Biometrika 1997. 84:737-743 .
- A sequential trial of pain killers in arthritis: Issues of multiple comparisons with control and of interval-censored survival data. Journal of Biopharmaceutical Statistics 1997. 7:333-353 .
- Sequential designs for equivalence studies. Statistics in Medicine 1996. 15:2703-2715 .
- Point and interval estimation following a sequential clinical trial. Biometrika 1996. 83:453-461 .
- A parametric multistate model for the analysis of carcinogenicity experiments. Lifetime Data Analysis 1995. 1:327-346 .
- Bayesian decision procedures for dose determining experiments (Disc: p897-899). Statistics in Medicine 1995. 14:885-893 .
- BAYESIAN DECISION PROCEDURES FOR DOSE DETERMINING EXPERIMENTS. Statistics in Medicine 1995. 14:885-893 .
- Sample sizes for phase II clinical trials derived from Bayesian decision theory. Statistics in Medicine 1994. 13:2493-2502 .
- Sequential methods based on the boundaries approach for the clinical comparison of survival times. Statistics in Medicine 1994. 13:1357-1368 .
- Sample sizes for phase ii clinical trials derived from Bayesian decision theory†. Statistics in Medicine 1994. 13:2493-2502 .
- Sequential methods based on the boundaries approach for the clinical comparison of survival times (Disc: p1369-1370). Statistics in Medicine 1994. 13:1357-1368 .
- Sample size calculations for ordered categorical data. Statistics in Medicine 1993. 12:2257-2271 .
- Reply to comment on ``A random effects model for ordinal responses from a crossover trial'' (V10 p901-907). Statistics in Medicine 1993. 12:2150-2151 .
- The case for frequentism in clinical trials (Disc: p1415-1419). Statistics in Medicine 1993. 12:1405-1413 .
- The case for frequentism in clinical trials. Statistics in Medicine 1993. 12:1405-1413 .
- A random effects model for ordinal responses from a crossover trial. by F. Ezzet and J. Whitehead, Statistics in Medicine, 10, 901–907 )1991(. Statistics in Medicine 1993. 12:2147-2151 .
- Sample size calculations for ordered categorical data (Corr: 94V13 p871). Statistics in Medicine 1993. 12:2257-2271 .
- A random effects model for binary data from crossover clinical trials. Applied Statistics 1992. 41:117-126 .
- Estimating the ventilation-perfusion distribution: An ill-posed integral equation problem. Biometrics 1992. 48:175-187 .
- Overrunning and underrunning in sequential clinical trials. Controlled Clinical Trials 1992. 13:106-121 .
- Teaching statistical inference within applied statistics. .
- A random effects model for ordinal responses from a crossover trial. Statistics in Medicine 1991. 10:901-907 .
- A general parametric approach to the meta-analysis of randomized clinical trials. Statistics in Medicine 1991. 10:1665-1677 .
- Analysis of failure time data with ordinal categories of response. Statistics in Medicine 1991. 10:1703-1710 .
- A random effects model for ordinal responses from a crossover trial (Disc: p906-907). Statistics in Medicine 1991. 10:901-906 .
- Sequential methods in clinical trials. .
- The impact that group sequential tests would have made on ECOG clinical trials. Gary Rosner and Anastasios A. Tsiatis, Statistics in Medicine, 8, 505–516 (1989). Statistics in Medicine 1990. 9:853-854 .
- An improved approximation for calculation of confidence intervals after a sequential clinical trial (Corr: V10 p1001). Statistics in Medicine 1990. 9:1277-1285 .
- The double triangular test: A sequential test for the two-sided alternative with early stopping under the null hypothesis. Sequential Analysis 1990. 9:117-136 .
- Comments on ``The impact that group sequential tests would have made on ECOG clinical trials'' (V8 p505-516). Statistics in Medicine 1990. 9:853-854 .
- An improved approximation for calculation of confidence intervals after a sequential clinical trial. Statistics in Medicine 1990. 9:1277-1285 .
- The analysis of relapse clinical trials, with application to a comparison of two ulcer treatments. Statistics in Medicine 1989. 8:1439-1454 .
- Sequential methods for monitoring declining quality, with application to the long-term storage of seeds. Biometrics 1989. 45:13-22 .
- Models for nested binary and ordinal data. .
- Comparison of the information in two lung function experiments. Statistics in Medicine 1989. 8:861-870 .
- Comparison of the information in two lung function experiments†. Statistics in Medicine 1989. 8:861-870 .
- Prospective epidemiological studies involving paired organs. Statistics in Medicine 1988. 7:619-625 .
- Supplementary analysis at the conclusion of a sequential clinical trial. Biometrics 1986. 42:461-471 .
- On the bias of maximum likelihood estimation following a sequential test. Biometrika 1986. 73:573-581 .
- Sample sizes for phase II and phase III clinical trials: An integrated approach. Statistics in Medicine 1986. 5:459-464 .
- A FORTRAN program for the design and analysis of sequential clinical trials. Computers and Biomedical Research 1985. 18:176-183 .
- Comments on ``The search for optimality in clinical trials''. International Statistical Review 1985. 53:34-35 .
- Designing phase II studies in the context of a programme of clinical research. Biometrics 1985. 41:373-383 .
- Comments on ``On the allocation of treatments in sequential medical trials''. International Statistical Review 1985. 53:34-35 .
- Fitting survival models using GLIM. .
- Group sequential clinical trials with triangular continuation regions (Corr: V39 p1137). Biometrics 1983. 39:227-236 .
- The use of the sequential probability ratio test for monitoring the percentage germination of accessions in seed banks. Biometrics 1981. 37:129-136 .
- Fitting Cox's regression model to survival data using GLIM. Applied Statistics 1980. 29:268-275 .
- The analysis of sequential clinical trials. Biometrika 1979. 66:443-452 .
- Sequential rank and the Polya urn. Journal of Applied Probability 1979. 16:213-219 .
- Sequential forms of the log rank and modified Wilcoxon tests for censored data (Corr: V68 p576). Biometrika 1979. 66:105-114 .
- Large sample sequential methods with application to the analysis of $2 × 2$ contingency tables. Biometrika 1978. 65:351-356 .
- A sequential test for certain composite hypotheses. Journal of the Royal Statistical Society, Series B: Methodological 1975. 37:198-204 .